The ADAMs family of proteases: new biomarkers and therapeutic targets for cancer?

Table 2 Selective ADAM inhibitors

Inhibitor	Target ADAM	Company	Refs
INCB3619	10, 17	Incyte, Wilmington, DE	[32–34]
INCB7839	10,17	Incyte	[34, 70–72]
WAY-022	17	Wyeth-Aherst, Pearl River, NY	[73]
GI254023X	10	Glaxo Smith Kline	[74]
GW280264X	10,17	Glaxo Smith Kline	[74]
TMI-2	17	Pfizer	[75]
KB-R7785	12	Organon, Osaka, Japan	[80]

ISSN: 1559-0275