Skip to main content
Fig. 7 | Clinical Proteomics

Fig. 7

From: Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Fig. 7

Functional annotation categories calculated in DAVID (DAVID Bioinformatics Resources 6.7, National Institute of Allergy and Infectious Diseases) of correlating genes upregulated by TGFβ (EMT genes) to proteins up-regulated in brain metastasis of melanoma patients treated with BRAF and MEK inhibitors (see Additional file 4: Table S2 for full list of overlapping data between TGFβ induced signature in Microarray data and shotgun proteomics data in cerebral melanoma metastases). Fold enrichment values, count (genes involved in the term), p value and FDR (false discovery rate, calculated using the Benjamini–Hochberg procedure), listed next to the graph, were calculated using DAVID bioinformatics resources

Back to article page