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Table 3 Linear range of method response by surrogate peptides TLLLQIAK and NITEIADLTQK

From: Development of an ID-LC–MS/MS method using targeted proteomics for quantifying cardiac troponin I in human serum

Parameters

TLLLQIAK

NITEIADLTQK

Optimum range for cTnI (μg/L)

0.7–23.3

0.7–23.3

Regression equation

Yratio peak area = 2.6219CcTnI-2.3795

Yratio peak area = 1.7415CcTnI − 1.2778

Correlation Coefficient

0.996

0.992

LOQ of cTnI (μg/L)

1.8

4.8

LOD of cTnI (μg/L)

0.6

1.6