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Fig. 3 | Clinical Proteomics

Fig. 3

From: Prognostic biomarker discovery based on proteome landscape of Chinese lung adenocarcinoma

Fig. 3

Characteristics of solid-predominant adenocarcinomas. A Kaplan–Meier curve of overall survival in SOL and non-SOL adenocarcinoma samples. B Pathway enriched in SOL or the rest tumor samples based on GSEA. Enrichment ratio > 0 indicated the pathway was enriched in SOL samples; Enrichment ratio < 0 indicated the pathway was enriched in the rest tumor samples. C Differentially expressed proteins between SOL and non-SOL adenocarcinoma samples. A criteria of p < 0.05 and abs (log2 fold change) > 2 was applied to define significantly up- or down- regulated proteins. D Differentially expressed proteins which were significantly correlated with prognosis. Top panel: protein expression level in SOL and non-SOL adenocarcinoma samples. Bottom panel: Kaplan–Meier curve of overall survival in samples with high expression (red line) and low expression (blue line) of the same protein presented in the top panel

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