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Fig. 3 | Clinical Proteomics

Fig. 3

From: Comparison of early changes in tear film protein profiles after small incision lenticule extraction (SMILE) and femtosecond LASIK (FS-LASIK) surgery

Fig. 3

Differences between preoperative and 1.5-hours postoperative tear protein levels for SMILE (A, B) and FS-LASIK (C, D). Volcano plots visualize the statistically significant proteins based on log2 fold change (x-axis) and adjusted p-value (y-axis) when preoperative and immediate postoperative tear levels are compared for SMILE (A) and FS-LASIK (C). The proteins down- and upregulated 1.5 h after the surgery in comparison to the preoperative time point are colored blue and orange, respectively. The five most up- and downregulated proteins are further labeled for both surgery types. The top 10 activated and inhibited biological functions associated with the statistically significant proteins are visualized by dotplots for SMILE (B) and FS-LASIK (D)

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