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Table 3 ANCOVA analysis of differences in protein levels comparing SMILE vs. FS-LASIK treated eyes at different time points postoperatively

From: Comparison of early changes in tear film protein profiles after small incision lenticule extraction (SMILE) and femtosecond LASIK (FS-LASIK) surgery

Postoperative time point

Protein name

Gene name

Fold change (log2)

Adj. p-value

1,5 h

Keratin, type I cytoskeletal 9

KRT9

-1.63

0.043

 

Protein OS9

OS9

-0.84

0.030

 

Insulin-like growth factor-binding protein complex acid labile subunit

IGFALS

0.85

0.043

1 month

Alpha-1-antitrypsin

SERPINA1

-0.75

0.047

 

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

PLOD1

-0.97

0.045

 

Complement C1q subcomponent subunit C

C1QC

1.43

0.045

 

Cytosolic Fe-S cluster assembly factor NUBP2

NUBP2

1.22

0.045

  1. The fold change is negative, when protein level is higher in FS-LASIK group and positive, when protein level is higher in SMILE group